Some time after my first treatment with Campath-1H, I began to experience difficulties again. By 1996 my condition had worsened to such an extent that I was no longer confident driving and required the use of a wheelchair. With my employees unable to accommodate my disabilities, I was determined to continue working. This I achieved by setting up my own business at home.
I also received more treatment with Campath-1H. This time, however, the drug had little impact. The difficulty was that by now I had developed Parkinson's disease in addition to MS. While drugs partially alleviated my Parkinson’s symptoms, my health continued to undergo a gradual decline and I became increasingly reliant on a wheelchair. By late 2004, I could only walk a short distance with the aid of a frame. In 2005, I experienced a further crisis, suffering meningitis and then paralysis as a result of an abscess that pressed on my spinal cord in my neck. These complications, not considered to be related to my Campath-1H, nearly cost me my life. Over the next 6 months I found myself confined to hospital, with a steel halo screwed on to my head to stabilise the disease in my vertebrae. This was followed by another 12 months of rehabilitation in hospital.
When finally released from hospital, I was confined to a wheelchair, possessing movement in only one arm. No longer able to dress or feed myself, let alone do other daily routine activities, I was now totally reliant on the care of my husband and a carer coming into our home. In spite of all this, I was determined to continue working. This I did with the help of my husband for seven years.
Today I am a quadriplegic, but I believe Campath-1H helped slow down the progression of my MS and gave me the treasured bonus of 5 years more quality of life.