Timeline of key events in biotechnology

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This was announced at a Conference of Anatomists convened at the Wistar Institute1905-01-01T00:00:00+0000von Euler shared the 1970 Nobel Prize for Medicine for 'discoveries concerning the humoral transmittors in the nerve terminals and the mechanism for their storage, release and inactivation.'1905-02-07T00:00:00+0000Hitchings shared the 1988 Nobel Prize for Medicine for 'discoveries of important principles for drug treatment.'1905-04-18T00:00:00+0000Sterne pioneered a vaccine against anthrax which effectively wiped out the disease. He used Pasteur's methods to develop the vaccine. 1905-06-01T00:00:00+0000Flemming was the first to describe the behaviour of chromosomes during cell division, a process he called mitosis, and is credited as the founder of cytogenetics. 1905-08-04T00:00:00+0000An Australian virologist and physician, MacFarlane Burnet is most well known for his discovery of acquired immunological tolerance and demonstrating how the body recognises the difference between self and non-self. His work helped advance the development of vaccines, tissue transplantation, monoclonal antibodies and associated therapies. 1905-09-03T00:00:00+0000Chase discovered that white blood cells trigger the immune response in the body confronting a foreign invader. He laid the foundation for the discovery of lymphocyte cells and B and T cells.1905-09-17T00:00:00+0000A biochemist, Ochoa shared the 1959 Nobel Prize for Medicine for 'discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid.'1905-09-24T00:00:00+0000Nearly half of all rats now used in research are descendants from the WistarRat. 1906-01-01T00:00:00+0000Chain shared the 1945 Nobel Prize for Medicine for the discovery of penicillin.1906-06-19T00:00:00+0000Schaudinn was a German zoologist who helped discover the bacterial cause of syphilis. He also identified the amoeba that causes dysentry and confirmed hook worm infections are contracted through skin on the feet. 1906-06-22T00:00:00+0000A German biophysicist, Delbruck helped discover how viruses replicate their genetic structure, showing that bacterial resistance from viruses is due to random mutation and not the result of adaptive changes. 1906-09-04T00:00:00+0000Leloir, an Argentinian physician and biochemist, won the 1970 winner of the Nobel Prize for Chemistry for 'his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates.' 1906-09-06T00:00:00+0000Reuben Ottenberg carries out the first successful blood transfusion using blood typing and cross-matching based on the use of antisera. 1907-01-01T00:00:00+0000Bovet won the 1957 Nobel Prize for Medicine for discovering 'synthetic compounds that inhibit the action of certain bodily substances, especially their action on the vascular system and the skeletal muscles.'1907-03-23T00:00:00+0000Pirie helped determine that the genetic component of viruses was RNA. Before this viruses were thought to be made up completely of proteins. 1907-07-01T00:00:00+0000A Scottish biochemist, Todd helped elucidate the structure and synthesis of many of the building blocks of DNA and RNA: nucleotides, nucleosides and their co-enzymes. He also synthesised two important biochemical compounds: adenosine triphosphate (ATP) and flavin adenine dinucleotide (FAD). 1907-10-02T00:00:00+0000Hamilton was a medical physicist who pioneered the use of radioistopes for treating and diagnosing disease. He found radioactive iodine particularly useful in the diagnosis and treatment of thyroid disorders. 1907-11-11T00:00:00+0000The Russian histologist Alexander Maksimov proposes the term 'stem cell' for scientific usage.1908-01-01T00:00:00+0000P Ehrlich, 'About the current state of carcinoma research', Lecture given to students at Amsterdam University, Association of Scientific work, 19081908-01-01T00:00:00+0000
Date Event People Places Sciences
1905Research made the principle objective of the Wistar Institute Wistar Institute 
7 Feb 1905Ulf von Euler was born in Stockholm, Swedenvon EulerKarolinska InstituteNeuroscience
18 Apr 1905George H Hitchings was born in Hoquiam, WA, USAHitchingsWellcome Research LaboratoriesPharmacology
1 Jun 1905Max Sterne was born in Trieste, AustriaSterneOnderstepoort Veterinary Research InstituteVaccine
4 Aug 1905Walther Flemming diedFlemmingUniversity of KielCell, Genetics
3 Sep 1905Frank Macfarlane Burnet was born in Traralgon, AustraliaBurnettWalter and Eliza Hall InstituteImmunology, Vaccine
17 Sep 1905Merrill W Chase born in Providence, RI, USAChaseRockefeller UniversityAntibodies
24 Sep 1905Severo Ochoa was born in Luarca, SpainOchoaNew York UniversityGenetics, DNA
1906Creation of the first standardised animal model for research - the WistarRat Wistar Institute 
19 Jun 1906Ernst B Chain was born in Berlin, GermanyChainOxford UniversityAntibacterial agents
22 Jun 1906Fritz R Schaudinn diedSchaudinnCharite – Universitatsmedizin BerlinBacteriology
4 Sep 1906Max Delbruck was born in Berlin, GermanyDelbruckCalifornia Institute of TechnologyGenetics, Virology
6 Sep 1906Luis F Leloir was born in Paris, FranceLeloirInstitute for Biochemical ResearchBiochemistry
1907First successful blood transfusionOttenbergMount Sinai HospitalAntibodies
23 Mar 1907Daniel Bovet was born in Neuchatel, SwitzerlandBovetIstituto Superiore di Sanita Pharmacology
1 Jul 1907Norman Wingate (Bill) Pirie was born in Easeborn, UKPirie Rothamsted Experimental StationRNA, Virology
2 Oct 1907Alexander R Todd was born in Glasgow, ScotlandToddUniversity of ManchesterDNA
11 Nov 1907Joseph G Hamilton was born in the USAHamiltonUSA 
1908The term 'stem cell' is coinedMaximovPetrograd UniversityStem cells
1908Paul Ehrlich reports that spontaneously developed tumours can be suppressed by the immune system EhrlichGoettingen UniversityCancer immunotherapy

1905

Research made the principle objective of the Wistar Institute

7 Feb 1905

Ulf von Euler was born in Stockholm, Sweden

18 Apr 1905

George H Hitchings was born in Hoquiam, WA, USA

1 Jun 1905

Max Sterne was born in Trieste, Austria

4 Aug 1905

Walther Flemming died

3 Sep 1905

Frank Macfarlane Burnet was born in Traralgon, Australia

17 Sep 1905

Merrill W Chase born in Providence, RI, USA

24 Sep 1905

Severo Ochoa was born in Luarca, Spain

1906

Creation of the first standardised animal model for research - the WistarRat

19 Jun 1906

Ernst B Chain was born in Berlin, Germany

22 Jun 1906

Fritz R Schaudinn died

4 Sep 1906

Max Delbruck was born in Berlin, Germany

6 Sep 1906

Luis F Leloir was born in Paris, France

1907

First successful blood transfusion

23 Mar 1907

Daniel Bovet was born in Neuchatel, Switzerland

1 Jul 1907

Norman Wingate (Bill) Pirie was born in Easeborn, UK

2 Oct 1907

Alexander R Todd was born in Glasgow, Scotland

11 Nov 1907

Joseph G Hamilton was born in the USA

1908

The term 'stem cell' is coined

1908

Paul Ehrlich reports that spontaneously developed tumours can be suppressed by the immune system