This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

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Date Event People Places Sciences
Jul 1973Cesar Milstein and Dick Cotton report the successful fusion of two different myeloma cell lines, one from a mouse and the other from a ratCotton, MilsteinLaboratory of Molecular BiologyMonoclonal antibodies
12 Aug 1973Walter R Hess diedHessUniversity of ZurichNeuroscience
16 Aug 1973Selman A Waksman diedWaksmanRutgers UniversityAntibacterial agents
1974Regulation begins for recombinant genetic research  Recombinant DNA
1974First publication on inserting foreign DNA into miceJaenisch, MintzSalk Institute, Fox Chase Institute for Cancer ResearchTransgenic animals
1974The European Molecular Biology Laboratory is founded EMBL 
08 Feb 1974Immune surveillance theory that immune system provides protection against cancer discredited by research showing that 'Nude' mice lacking immune system function no more likely to develop tumours than normal miceStutmanMemorial Sloan-Kettering Cancer CenterImmunology, Immunotherapy, Oncology
09 Mar 1974Earl W Sutherland diedSutherlandVanderbilt UniversityCell
Jun 1974Georges Kohler joins Cesar Milstein's research team to investigate somatic mutation and antibody diversityKohler, MilsteinLaboratory of Molecular BiologyMonoclonal antibodies
Jul 1974First concerns about potential biohazards of recombinant DNA publishedBerg, Baltimore, Boyer, Cohen Recombinant DNA
1975Temporary moratorium on genetic engineeringBerg Recombinant DNA
Jan 1975Unlimited long-surviving monoclonal antibodies createdMilstein, KohlerLaboratory of Molecular BiologyMonoclonal antibodies
1975Short-lasting antibodies against influenza virus devisedGerhardWistar InstituteMonoclonal antibodies
1975 - 1979First monoclonal antibody created to target a neurotransmitter peptideMilstein, CuelloLaboratory of Molecular Biology, MRC Neurochemical Pharmacology Unit, Oxford UniversityMonoclonal antibodies
1975A liquid media is developed for growing bone marrow cells, including the blood stem cellDexterPaterson Institute for Cancer ResearchStem cells
1975Sanger and Coulson publish their plus minus method for DNA sequencingSanger, CoulsonLaboratory of Molecular BiologySequencing DNA
Feb 1975Natural killer cell identified in mice and shown to be important part of immune systemKiessling, Klein, Pross, WigzellKarolinska InstituteImmunology, Immunotherapy, Oncology
15 Apr 1975Human natural killer cell isolatedJondal, ProssKarolinska InstituteImmunology, Immunotherapy, Oncology
19 Apr 1975Percy Lavon Julian diedJulianHarvard UniversityPharmacology
24 Apr 1975Discovery of unique molecular marker, idiotype, on blood cancer cells, opening new avenue for cancer diagnosis and therapyStevensonTenovus Research LaboratoryImmunology, Immunotherapy, Oncology

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