This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

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Date Event People Places Sciences
Dec 1985Cetus Corporation and Perkin-Elmer partnered to develop instruments and reagents for PCR Cetus CorporationPCR
Dec 1985Experiments with plasmids indicate double-strand break technique efficient for gene editing in mammalian cellsJasin, de Villiers, Weber, SchaffnerUniversity of ZurichGene editing
Dec 1985IL-2 based immunotherapy shown to reduce tumours in patients with melanoma and renal cell cancerRosenbergNational Cancer InstituteImmunology, Immunotherapy, Oncology
Dec 1985New transgenic mouse model developed to study cancer, opening up the possibility of studying oncogene cooperation and the efficacy of novel anti-cell signal drugs for lymphoma therapyAdams, Harris, Pinkert, Corcoran, Alexander, Cory, Palmiter, BrinsterWalter and Eliza Hall Institute, University of Pennsylvania, Howard Hughes Medical InstituteTrangenic animals, Oncology
20 Dec 1985The Polymerase Chain Reaction technique was publishedMullisCetus CorporationPCR, Sequencing DNA
1986National Marrow Donor Programme established in US  Stem cells
1986First machine developed for automating DNA sequencingHood, Smith, HunkapillerCalifornia Institute of Technology, Applied BiosystemsSequencing DNA, Genomics
1986Discovery of RNA interference (RNAi)Jorgensen, NapoliAdvanced Genetic SciencesRNA interference
14 Feb 1986Gene targeting technique used to correct defective gene in the chromosome of a mammalian cellThomas, Folger, CapecchiUniversity of UtahGene editing
Apr 1986Human Genome Organization founded  Sequencing DNA, Genomics
May 1986First humanised monoclonal antibody createdDear, Foote, Jones, Neuberger, WinterLaboratory of Molecular BiologyMonoclonal antibodies, Recombinant DNA
Jun 1986Interferon approved for treating hairy cell leukaemia  Recombinant DNA, Monoclonal antibodies
Jun 1986First monoclonal antibody drug approvedChang, Kung, Gringas, Schlossman, Goldstein  Monoclonal antibodies
Jun 1986Co-ordinated US regulatory framework esablished for biotechnology  Regulation
Jul 1986First recombinant vaccine licensed Merck & CoRecombinant DNA, Vaccine
24 Jul 1986Fritz A Lipmann diedLipmann Nutrition
22 Oct 1986Albert Szent-Gyorgyi von Nagyrapolt diedSzent-Gyorgyi Szeged UniversityCell
Dec 1986Anti-tumour responses observed in 3 out of 10 patients given high-doses of Interleukin-2 (IL-2) Rosenberg, Lotze, Chang, Seipp, Simpson, VettoNational Cancer InstituteImmunology, Immunotherapy, Oncology
30 Dec 1986Reinhold Benesch diedBeneschColumbia UnivesityBiochemistry
1987First clinical trials of foetal neural cell grafting in patients with Parkinson’s diseaseBjorklund, Lindvall Lund UniversityStem cells

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