This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

To search for particular terms in the description of the event enter the term in the box below 'Event' on the table and press 'enter'. Alternatively use the dropdown lists to filter by Person, Place or Science. Click here to clear the filter.

Date Event People Places Sciences
1987 - 1989Scientists lay the foundation for the cloning of human tumour antigens recognised by cytotoxic T lymphocytes, a type of white blood cell that kills cancer cellsDe Plaen, BoonLudwig Institute for Cancer ResearchImmunology, Immunotherapy, Oncology
Jan 1987Jean-Francoise Brunet and colleagues discovered the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)Brunet, Denizot, Luciani, Roux-Dosseto, Suzan, Matte, Golstein  
15 Mar 1987First stable human anti-tumour cytotoxic T cell clones isolated and maintained in cultureHerin, Lemoine, Weynants, Vessiere, Van Pel, Knuth, Devos, BoonLudwig InstituteImmunology, Immunotherapy, Oncology
Apr 1987CD8 coreceptor proven to be actively involved in antigen recognition by killer T cellsDembic, Haas, Zamoyska, Parnes, Steinmetz, von BoehmerBasel Institute of ImmunologyImmunology, Immunotherapy, Oncology
09 Apr 1987Successful results reported for trial using the cytokine IL-2 and lymphokine-activated killer cells to treat cancerRosenbergNational Cancer InstituteImmunotherapy
May 1987John H Northrop diedNorthrop  
Jun 1987The patent for PCR with Taq ploymerase is filedMullis  
Jul 1987Identification of the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)Brunet, Denizot, Luciani, Roux-Dosseto, Suzan, Mattei, GolsteinINSERM-CNRSImmune checkpoint inhibitors, Immunology, Immunotherapy, Oncology
02 Oct 1987Peter Medawar diedMedawarUniversity College LondonImmunology
06 Nov 1987Publication of gene targeting technique for targetting mutations in any geneThomas, CapecchiUniversity of UtahGene editing, Transgenic animals
Nov 1987First evidence provided for the interaction between the surface molecule CD4 and major histocompatibility class IIDoyle, StromingerHarvard UniversityImmunology, Immunotherapy, Oncology
Dec 1987Discovery of CRISPR mechanismAmemura, Ishino, Makino, Nakata, Shinagawa, Takase, WachiOsaka UniversityCRISPR, Gene editing
02 Dec 1987Luis F Leloir diedLeloirInstitute for Biochemical ResearchBiochemistry
1988First reported clinical use of umbilical cord bloodBroxmeyerIndiana UniversityStem cells
1988Campath-1H is created - the first clinically useful humanised monoclonal antibody.Winter, Waldmann, Reichmann, ClarkCambridge University, Laboratory of Molecular BiologyMonoclonal antibodies, Recombinant DNA, Campath
1988Patent application filed for a method to create transgenic mice for the production of human antibodiesBruggeman, Caskey, Neuberger, Surani, Teale, Waldmann, WilliamsLaboratory of Molecular Biology, Babraham Institute, Cambridge UniversityMonoclonal antibodies, gene cloning, transgenic animals
1988US Congress funds genome sequencing  Sequencing DNA, Genomics
21 Mar 1988Patrick Steptoe diedSteptoe Reproduction
Apr 1988Development of first rapid search computer programme to identify genes in a new sequencePearson, Lipman Sequencing DNA, Genomics
Apr 1988OncoMouse patent grantedLeder, StewartHarvard UniversityTransgenic animals

Website design by Silico Research the creative minds behind BioPartnering.

Follow us to keep up with all the new content about the world of biotechnology.