This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

To search for particular terms in the description of the event enter the term in the box below 'Event' on the table and press 'enter'. Alternatively use the dropdown lists to filter by Person, Place or Science. Click here to clear the filter.

Date Event People Places Sciences
30 Sep 1994Andre Michel Lwoff diedLwoffPasteur InstituteMicrobiology, Virology
07 Oct 1994Niels Kaj Jerne diedJerneBasel Institute for ImmunologyImmunology, Monoclonal antibodies
03 Nov 1994Ralph W G Wyckoff diedWyckoffRockefeller UniversityBacteriology, Virology
Dec 1994Second monoclonal antibody drug approvedCollerStony Brook University, CentocorMonoclonal antibodies
1994First chimeric monoclonal antibody therapeutic approved for marketCollerCentocor, State University of New YorkMonoclonal antibodies, Recombinant DNA
Dec 1994Breaks made in a double-strand of DNA in a mouse chromosome for the first time using a rare-cutting endonuclease, I-Scel. The method lays the foundation for a new technique for targeted genome modification using double-stranded breaks instead of plasmids.Rouet, Smih, JasinSloan-Kettering Institute, Cornell UniversityGene editing
1995First monoclonal antibody drug for cancer approved in EuropeKoprowski Monoclonal antibodies
1995First derivation of primate embryonic stem cell lines   Stem cells
1995First monoclonal antibody therapeutic for cancer approved for marketKoprowskiWistar Institute, CentocorMonoclonal antibodies
1995US licensed first wildlife rabies vaccine Wistar InstituteVaccine, Virology
18 Jan 1995Adolf F J Butenandt diedButenandt Endocrinology
01 Mar 1995Georges Kohler diedKohlerLaboratory of Molecular BiologyMonoclonal antibodies
14 May 1995Christian B Anfinsen died AnfinsenNational Institutes of HealthRNA
23 Jun 1995Jonas Salk diedSalkUniversity of PittsburghVirology, Vaccine
Jul 1995Craig Venter's team at The Institute of Genomics Research (TIGR) published the first complete sequence of the 1.8 Mbp genome of a free-living organism (the bacterium Haemophilus influenzae)VenterThe Institute for Genomic ResearchSequencing DNA, Genomics
01 Aug 1995Identification of regulatory T cells (CD4+CD25+) and their role in protecting against autoimmunity  Immunology
Nov 1995FDA lifted special restrictions on biotechnology drugs   
1996Complete genome sequence of the first eukaryotic organism, the yeast S. cerevisiae, is published   Sequencing DNA, Genomics
1996First reports that blood stem cell might be able to give rise to cells other than those of the blood systemBlau, Lagasse, Lemischka, Morrison, Thiese, Krause, Gussoni, Bjornson Stem cells
1996Pyrosequencing is introduced for DNA sequencingRonaghi, NyrenRoyal Institute of TechnologySequencing DNA, Genomics

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