This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

To search for particular terms in the description of the event enter the term in the box below 'Event' on the table and press 'enter'. Alternatively use the dropdown lists to filter by Person, Place or Science. Click here to clear the filter.

Date Event People Places Sciences
1994First transgenic mice strains reported for producing human monoclonal antibodiesBruggemann, Green, Lonsberg, NeubergerCell Genesys, GenPharm, Laboratory of Molecular BiologyMonoclonal antibodies, Transgenic animals, Gene cloning
09 Feb 1994Howard M Temin diedTeminUniversity of WisconsinGenetics, Virology, Oncology
1994 - 1995Identification and characterisation of the natural killer T cell, a lymphocyte able to bind and kill certain tumour and virus-infected cellsBendelacUniversity of ChicagoImmunology, Immunotherapy, Oncology
17 Apr 1994Roger W Sperry diedSperryCalifornia Institute of TechnologyNeuroscience
1994Experiments in adult rats indicate olifactory ensheathing cells could regenerate injured dorsal root axons in spinal cordRamon-Cueto, Nieto-SampedroInstituto CajalStem cells
Jul 1994DNA structure of p53-DNA elucidatedCho, Gorina, Jeffrey, PavletichMemorial Sloan-Kettering Cancer CenterOncology, p53
27 Jul 1994Dorothy Crowfoot Hodgkin diedHodgkinShipston-on-Stour, Warwickshire, UKX-ray crystallography
29 Jul 1994Dorothy M Crowfoot Hodgkin diedHodgkinOxford UniversityBiochemistry, X ray crystallography
18 Aug 1994Richard Laurence Millington Synge diedSyngeRowett Research InstituteAnalytical chemistry
19 Aug 1994Linus C Pauling diedPaulingCalifornia Institute of TechnologyGenetics
30 Sep 1994Andre Michel Lwoff diedLwoffPasteur InstituteMicrobiology, Virology
07 Oct 1994Niels Kaj Jerne diedJerneBasel Institute for ImmunologyImmunology, Monoclonal antibodies
03 Nov 1994Ralph W G Wyckoff diedWyckoffRockefeller UniversityBacteriology, Virology
Dec 1994Second monoclonal antibody drug approvedCollerStony Brook University, CentocorMonoclonal antibodies
1994First chimeric monoclonal antibody therapeutic approved for marketCollerCentocor, State University of New YorkMonoclonal antibodies, Recombinant DNA
Dec 1994Breaks made in a double-strand of DNA in a mouse chromosome for the first time using a rare-cutting endonuclease, I-Scel. The method lays the foundation for a new technique for targeted genome modification using double-stranded breaks instead of plasmids.Rouet, Smih, JasinSloan-Kettering Institute, Cornell UniversityGene editing
1995First monoclonal antibody drug for cancer approved in EuropeKoprowski Monoclonal antibodies
1995First derivation of primate embryonic stem cell lines   Stem cells
1995First monoclonal antibody therapeutic for cancer approved for marketKoprowskiWistar Institute, CentocorMonoclonal antibodies
1995US licensed first wildlife rabies vaccine Wistar InstituteVaccine, Virology

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