This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

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Date Event People Places Sciences
Jun 2000Human genome draft sequence announced  Sequencing DNA, Genomics
01 Sep 2000 Experiments show zinc finger nucleases can create double-stranded DNA breaks in cellsSmith, Bibikova, Whitby, Reddy, Chandrasegaran, Carroll Johns Hopkins University, University of Utah, Pondicherry UniversityGene editing, Zinc fingers
Oct 2000PD-1 protein shown to be important mechanism in dampening down the immune responseFreeman, Long, IwaiDana-Farber Cancer InstituteImmune checkpoint inhibitors
04 Oct 2000Michael Smith died University of British ColumbiaRecombinant DNA, Monoclonal antibodies
15 Oct 2000Konrad Bloch diedBlochHarvard UniversityBiochemistry
Dec 2000First plant DNA sequenced  Sequencing DNA, Genomics
2001The Stem Cell Network is formed   Stem cells
2001Dermal stem cells identified in adult skin tissue   Stem cells
Feb 2001First consensus sequence of human genome published CeleraSequencing DNA
Mar 2001Mechanism uncovered for the way the immune system generates regulatory T-cellsJordanWistar InstituteImmunology
May 2001RNAi demonstrated to be useful genetic toolElbashir, Harborth, Lendecker, Yalcin, Weber, TuschlMax-Planck-Institute for Biophysical ChemistryRNA interference
Aug 2001US places restricitions on embryonic stem cell research  Stem cells
02 Sep 2001Christiaan Barnard diedBarnardUniversity of Cape TownTransplantation
Oct 2001Human embryo cloned to make stem cells Advanced Cell TechnologyStem cells, gene cloning
2002Complete genome sequence of the first mammalian model organism, the mouse, is published   Sequencing DNA
2002International Society for Stem Cell Research (ISCF) established  Stem cells
2002First complete purification of multipotent marrow stem cells from mice  Stem cells
2002Suspensiion of French gene therapy trials for treating SCID children  Gene therapy
2002T-cell immunoglobulin and mucin-domain containing-3 (TIM-3) discovered  Immune checkpoint inhibitors,
06 Feb 2002Max F Perutz diedPerutzLaboratory of Molecular BiologyBiochemistry

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