This website provides a curated collection of resources about the people, places and technologies that have enabled biotechnology to transform our healthcare and the world we live in today

Timeline of key events

Timeline of key events in biotechnology

To search for particular terms in the description of the event enter the term in the box below 'Event' on the table and press 'enter'. Alternatively use the dropdown lists to filter by Person, Place or Science. Click here to clear the filter.

Date Event People Places Sciences
28 Jul 2004Francis H C Crick diedCrickLaboratory of Molecular BiologyDNA, Genetics
15 Aug 2004Sune K Bergstrom diedBergstromKarolinska InstituteBiochemistry
13 Sep 2004Luis Ernesto Miramontes died   
05 Oct 2004Maurice H F Wilkins diedWilkinsKing's College LondonDNA, Genetics
11 Oct 2004David Murray died in La Garde-Freinet, FranceMurray  
19 Nov 2004John Robert Vane diedVaneUniversity of LondonPharmacology
Dec 2004First plant genome modified with Zinc finger method. Illustrates tool can be used to make targeted modifications in experimental organisms for gene functional studies and creating models of human genetic diseases.Lloyd, Plaisier, Carroll, DrewsUniversity of UtahGene editing, Zinc fingers
Dec 2004Autar Singh Paintal died   
Dec 2004First DNA microarray diagnostic device approved  Sequencing DNA, Genomics, Mircoarray chip
26 Dec 2004James Francis -'Frank' Pantridge died   
29 Dec 2004Julius Axelrod diedAxelrodNational Institutes of HealthNeuroscience
2005Lasker Prize awarded to James Till and Ernest McCullochTill, McCulloch Stem cells
2005First evidence for human bone cancer stem cells   Stem cells
2005UK Pattison Report emphasizes stem cells as likely potential therapies for the future  Stem cells
2005p53 shown to regulate metabolismFeng, Zhang, Levine, Jin, Jones, Plas, Kubek, Buzzai, Mu, Xu, Birnbaum, ThompsonCancer Institute of New Jersey, University of Pennsylvaniap53
Feb 2005Enzyme Ubp10 demonstrated to protect the genome from potential destabilising molecular eventsBerger, EmreWistar InstituteDNA, Genetics
03 Apr 2005Zinc finger method reported capable of modifying some genes in the human genome, laying the foundation for its use as tool to correct genes for monogenic disordersUrnov, Miller, Lee, BeausejourSangamo BioSciences, University of Texas Southwester Medical CenterGene therapy, Gene editing, Zinc fingers
Jun 2005Canadian researchers created the country's first embryonic stem cell linesNagySamuel Lunenfeld Research InstituteStem cells
Aug 2005French scientists suggest CRISPR spacer sequences provide cell immunity against phage infection and are a means of degrading DNABolotin, Quinquis, Sorokin, EhrlichInstitut National de la Recherche AgronomiqueCRISPR-Cas9, Gene editing
Aug 2005Adult skin cells reprogrammed to be like embryonic stem cellsCowan, Eggen, Melton, AtienzaHarvardStem cells

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