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Timeline of key events

Cambridge University: Timeline of key events

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Date Event People Places Sciences
20 Jun 1861Frederick Gowland Hopkins was born in Eastbourne, United KingdomHopkinsCambridge UniversityBiochemistry
05 Feb 1914Alan Lloyd Hodgkin was born in Banbury, United KingdomHodgkinCambridge UniversityNeuroscience
1936 - 1940Sanger takes degree in Natural Sciences at Cambridge UniversitySangerCambridge UniversityDNA Sequencing
1940 - 1943Sanger studies for a doctorate at Cambridge UniversitySangerCambridge UniversityDNA Sequencing
1942'Epigenetics' coined as a term to describe how genes interact with the environment to produce the physical traits of an organism WaddngtonCambridge UniversityEpigenetics
1944Sanger starts working on amino acid composition of insulinSangerCambridge UniversityDNA Sequencing
16 May 1947Frederick Gowland Hopkins diedHopkinsCambridge UniversityBiochemistry
1955Sanger completes the full sequence of amino acids in insulinSangerCambridge UniversityDNA Sequencing
1957Victor Ingram breaks the genetic code behind sickle-cell anaemia using Sanger's sequencing techniqueIngram, SangerCambridge UniversityDNA Sequencing
1957Conrad Waddington develops model of epigenetic landscape to show the process of cellular decision-making during biological developmentWaddngtonCambridge UniversityEpigenetics, Embryology
1958Sanger awarded his first Nobel Prize in ChemistrySangerCambridge UniversityDNA Sequencing
1960Sanger begins to devise ways to sequence nucleic acids, starting with RNASangerCambridge UniversityDNA Sequencing
22 Apr 1961Genes linked to X-chromosome inactivation in female mice embyosLyonCambridge UniversityEpigenetics, Embyology
1962Nuclei from adult frog cells reprogrammed to full embryonic potential after transfer into frog eggsGurdon, AltmanCambridge UniversityStem cells
1978Transplantable stem cells discovered in human cord bloodEvansCambridge UniversityStem cells
1980First monoclonal antibodies developed against T-cells which can also activate human complement.Waldmann, Cobbold, Hale, Metcalfe. Watt, TrangCambridge UniversityMonoclonal antibodies, Campath
1981First embryonic stem cells identified in mice EvansCambridge UniversityStem cells
09 Jul 1981Mouse embryonic stem cells first isolated and cultured in the laboratoryEvans, Kaufman, MartinCambridge University, UCSFStem cells
1988Campath-1H is created - the first clinically useful humanised monoclonal antibody.Winter, Waldmann, Reichmann, ClarkCambridge University, Laboratory of Molecular BiologyMonoclonal antibodies, Recombinant DNA, Campath
1988Patent application filed for a method to create transgenic mice for the production of human antibodiesBruggeman, Caskey, Neuberger, Surani, Teale, Waldmann, WilliamsLaboratory of Molecular Biology, Babraham Institute, Cambridge UniversityMonoclonal antibodies, gene cloning, transgenic animals

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