Appendix 6: Database of tweets relating to COG-UK
This is an archive of tweets sent by people involved in or adjacent to COG-UK sent between 31st December 2019 to 31st December 2021. 31st December 2019 is the date on which the World Health Organization was informed of a cluster of cases of pneumonia of unknown cause detected in Wuhan City, Hubei Province, China. It is also the date of the first English language tweet, from Dal L Yang, a professor at University of Chicago, mentioning the coronavirus. The search is limited to the following terms: COG-UK, coronavirus, Covid-19, Covid19, nCov nCoV-2019, SARS-Cov-2, pathogen, variant or sequence. The archive currently contains 52,632 tweets. The tweets are presented in chronological order.
All the tweets
@devisridhar Worrying,epidemiology,season,New Year & Chinese New Year in 3weeks-but sorting out causative pathogen from huge number potential causes difficult interpret samples real challenge-critical to implement public health measures urgently & transparently share cause when 100% confirmed
2 Retweets 3 Likes
If the causative pathogen of the pneumonia cases in Wuhan turns out to be a new type of #coronavirus, you don’t need to be so surprised. https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006698
0 Retweets 2 Likes
@MackayIM In this news, a female senior lives in the vicinity and visits the market regularly, the XIEHE hospital tested for 10 known pathogens and can not identify the pathogen, and the patient has been transferred to JINYINTAN hospital after knowing her history (visited the market).
0 Retweets 2 Likes
Nick Loman @pathogenomenick@mstdn.science
@john_jxw That's true, although the likelihood of it being an entirely novel virus as opposed to a variant of a known virus are quite low.
0 Retweets 2 Likes
@onisillos @pathogenomenick Yes. Imagining you are about to shuffle ~13 billion people across the whole nation with significantly upgraded air and rail transportation within a month and an unknown pathogen is lingering there...epidemiology research in China needs to reach a new level.
1 Retweets 1 Likes
@WK_vetepi @pathogenomenick Don't get confused, the tech is one thing and great, but when the pathogen is unknown it is not that straightforward. Ask an expert on this @edwardcholmes #SMBE2019 Keynote. Viral metagenomics could certainly help, but again novel viruses cause big identification issues.
0 Retweets 0 Likes
Nick Loman @pathogenomenick@mstdn.science
@DrSimonHarris I guess that could hamper cross-border pathogen data sharing (athough shouldn't), but hopefully should not prevent sequencing and analysis of a new cluster of cases.
0 Retweets 0 Likes
The Wuhan Health Commission issued an official update on 05/01/2020 (Sunday night 20:33:24) for Wuhan pneumonia cluster. @arambaut Still no clear evidence of human-human transmission. But the pathogen is still not confirmed. https://wjw.wuhan.gov.cn/front/web/showDetail/2020010509020 translation in the link below.
3 Retweets 1 Likes
@HHV6_University It is not known to infect humans and that pathogen is also easy to identify.
0 Retweets 0 Likes
I’m watching this with mild concern - if a new pathogen is going to emerge very likely it will from Asia (population density ; high human / animal co-housing).
6 Retweets 26 Likes
@LairmoreDVMDean @Laurie_Garrett @CDC_NCEZID @edin_EID @InfectiousDz @APHAVPH @CAPublicHealth @CUGHnews @OneHealthUCD Numbers ~59, not trivial sort out causative pathogen from complex respiratory clinical samples & be sure of true cause.Clinical care,monitoring human-2-human transmission,infection control & classic epidemiology critical & sharing information as soon as possible with confirmation
1 Retweets 0 Likes
@OmicsOmicsBlog @thof82059134 @Clive_G_Brown @nanopore I don't think this is fair in the context of the original question. Yes homopolymers are a known issue. The platform hasn't changed for a (relatively) long time - R9.4 is still going strong. Bioinformatics weeds? Assembly and polishing pipelines for bacteria are well established.
1 Retweets 5 Likes
HBV-GLUE now live on the web -- a new resource for #HBV sequence data, based on #GLUEtools. https://t.co/qHbCNPE9b2 #hbvGlue
13 Retweets 22 Likes
@arambaut @EvolveDotZoo do any algorithms (protocols) exist to guide decision on your selection of next sample to sequence? reduce uncertainty in tree (where long branches are, @Hill_SarahC idea)? @NetworkArtic
1 Retweets 5 Likes
Willem van Schaik @wvschaik@mstdn.science
Amazing study by the group of Chang-Jun Cha on environmental metagenomics of the river Han (South Korea) ecosystem: 'Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance' https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-019-0774-7
6 Retweets 11 Likes
Nick Loman @pathogenomenick@mstdn.science
Apparently it might be a novel coronavirus. Sequence data should be released publicly immediately to aid diagnosis and surveillance.
20 Retweets 62 Likes
Latest news from state CCTV (China Central Television) news about the identity of the Wuhan pueminia cluster. A new form of #coronavirus is confirmed with sequencing and electron microscope. (via BJNEWS/???, 09/01/2020). Reference below. @arambaut @MackayIM
30 Retweets 36 Likes
@arambaut @MackayIM "On January 9th, the reporter learned from the preliminary evaluation of the pathogen from the expert team that as of 21:00 on January 7, 2020, A new type of coronavirus was detected, 2/n
3 Retweets 7 Likes
Made possible by the generous support of COVID-19 Genomics UK Consortium (COG-UK)
COG-UK was supported by funding from the Medical Research Council (MRC) part of UK Research & Innovation (UKRI), the National Institute of Health Research (NIHR) (grant code: MC_PC_19027), and Genome Research Limited, operating as the Wellcome Sanger Institute. This exhibition acknowledges use of data generated through the COVID-19 Genomics Programme funded by the Department of Health and Social Care. The views expressed are those of the author and not necessarily those of the Department of Health and Social Care or UKHSA.
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