Appendix 6: Database of tweets relating to COG-UK

This is an archive of tweets sent by people involved in or adjacent to COG-UK sent between 31st December 2019 to 31st December 2021. 31st December 2019 is the date on which the World Health Organization was informed of a cluster of cases of pneumonia of unknown cause detected in Wuhan City, Hubei Province, China. It is also the date of the first English language tweet, from Dal L Yang, a professor at University of Chicago, mentioning the coronavirus. The search is limited to the following terms: COG-UK, coronavirus, Covid-19, Covid19, nCov nCoV-2019, SARS-Cov-2, pathogen, variant or sequence. The archive currently contains 52,632 tweets. The tweets are presented in chronological order.

All the tweets

Worrying,epidemiology,season,New Year & Chinese New Year in 3weeks-but sorting out causative pathogen from huge number potential causes difficult interpret samples real challenge-critical to implement public health measures urgently & transparently share cause when 100% confirmed

2 Retweets 3 Likes

If the causative pathogen of the pneumonia cases in Wuhan turns out to be a new type of #coronavirus, you don’t need to be so surprised.

0 Retweets 2 Likes

In this news, a female senior lives in the vicinity and visits the market regularly, the XIEHE hospital tested for 10 known pathogens and can not identify the pathogen, and the patient has been transferred to JINYINTAN hospital after knowing her history (visited the market).

0 Retweets 2 Likes

That's true, although the likelihood of it being an entirely novel virus as opposed to a variant of a known virus are quite low.

0 Retweets 2 Likes

Yes. Imagining you are about to shuffle ~13 billion people across the whole nation with significantly upgraded air and rail transportation within a month and an unknown pathogen is lingering there...epidemiology research in China needs to reach a new level.

1 Retweets 1 Likes

Don't get confused, the tech is one thing and great, but when the pathogen is unknown it is not that straightforward. Ask an expert on this #SMBE2019 Keynote. Viral metagenomics could certainly help, but again novel viruses cause big identification issues.

0 Retweets 0 Likes

I guess that could hamper cross-border pathogen data sharing (athough shouldn't), but hopefully should not prevent sequencing and analysis of a new cluster of cases.

0 Retweets 0 Likes

The Wuhan Health Commission issued an official update on 05/01/2020 (Sunday night 20:33:24) for Wuhan pneumonia cluster. Still no clear evidence of human-human transmission. But the pathogen is still not confirmed. translation in the link below.

3 Retweets 1 Likes

It is not known to infect humans and that pathogen is also easy to identify.

0 Retweets 0 Likes

I’m watching this with mild concern - if a new pathogen is going to emerge very likely it will from Asia (population density ; high human / animal co-housing).

6 Retweets 26 Likes

Numbers ~59, not trivial sort out causative pathogen from complex respiratory clinical samples & be sure of true cause.Clinical care,monitoring human-2-human transmission,infection control & classic epidemiology critical & sharing information as soon as possible with confirmation

1 Retweets 0 Likes

I don't think this is fair in the context of the original question. Yes homopolymers are a known issue. The platform hasn't changed for a (relatively) long time - R9.4 is still going strong. Bioinformatics weeds? Assembly and polishing pipelines for bacteria are well established.

1 Retweets 5 Likes

HBV-GLUE now live on the web -- a new resource for #HBV sequence data, based on #GLUEtools. #hbvGlue

13 Retweets 22 Likes

do any algorithms (protocols) exist to guide decision on your selection of next sample to sequence? reduce uncertainty in tree (where long branches are, idea)?

1 Retweets 5 Likes

Amazing study by the group of Chang-Jun Cha on environmental metagenomics of the river Han (South Korea) ecosystem: 'Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance'

6 Retweets 11 Likes

Apparently it might be a novel coronavirus. Sequence data should be released publicly immediately to aid diagnosis and surveillance.

20 Retweets 62 Likes

Latest news from state CCTV (China Central Television) news about the identity of the Wuhan pueminia cluster. A new form of #coronavirus is confirmed with sequencing and electron microscope. (via BJNEWS/???, 09/01/2020). Reference below.

30 Retweets 36 Likes

"On January 9th, the reporter learned from the preliminary evaluation of the pathogen from the expert team that as of 21:00 on January 7, 2020, A new type of coronavirus was detected, 2/n

3 Retweets 7 Likes

and the whole genome sequence of the virus was obtained. A total of 15 cases of positive results of the new coronavirus were detected by the nucleic acid detection method. 3/n

2 Retweets 6 Likes

Respond to or comment on this page on our feeds on Facebook, Instagram, Mastodon or Twitter.