Metabolism

Metabolism: timeline of key events

Meyerhof was a physician and biochemist who was awarded the 1922 Nobel Prize in Physiology and Medicine for his discovery of the 'fixed relationship between the consumption of oxygen and the metabolism of lactic acid in the muscle.' In 1938 he was forced to flee Nazi Germany because of his Jewish background which entailed leaving the Kaiser Wilhelm Institute for Medicine where he was a director from 1929. He was appointed a guest professor at the University of Pennsylvania. 1884-04-12T00:00:00+0000Houssay was a physiologist who discovered how the pituitary gland regulates glucose or blood sugar levels. This he determined while studying the pituitary gland in dogs and toads during the early 1940s. In 1947 he was awarded the Nobel Prize for his achievement. He was the first Latin American to receive the Nobel Laureate in the sciences. The award was particularly poignant given that four years before the Argentinian military government had Houssay dismissed from his position at the University of Buenos Aires Medical school where he had built up an internationally respected department in experimental physiology and medicine from 1919. Houssay was later reinstated in 1955 following Juan Peron's fall from power. 1887-04-10T00:00:00+0000Gwei-djen was a biochemist who undertook pioneering work on metabolic pathways. In 1933, Gwei-djen took the bold decision to leave China, then isolated from the West, to study for a doctorate at Cambridge University where she remained for the rest of her career. By 1939 she had developed the first sensitive assay for detecting low levels of pyruvic acid, an intermediate involved in the breakdown of carbohydrates. Her work demonstrated that the levels of pyruvic acid could be raised by vitamin B1 deficiency and exercise. Gwei-djen worked closely with both Dorothy and Joseph Needham. Together with Joseph she compiled a series of books detailing Chinese achievements in science and technology.1904-07-22T00:00:00+0000The Cori's work helped identify the cyclical process that muscle cells use to make and store energy. Their insights into the process of sugar metabolism opened up new understandings of diabetes and the means to treat it. 1929-01-01T00:00:00+0000Meyerhof was a physician and biochemist who was awarded the 1922 Nobel Prize in Physiology and Medicine for his discovery of the 'fixed relationship between the consumption of oxygen and the metabolism of lactic acid in the muscle.' In 1938 he was forced to to flee Nazi Germany because of his Jewish background which entailed leaving the Kaiser Wilhelm Institute for Medicine where he was a director from 1929. He was appointed a guest professor at the University of Pennsylvania. 1951-10-06T00:00:00+0000Houssay was an Argentinian physiologist who discovered how the pituitary gland regulates glucose or blood sugar levels. This he determined while studying the pituitary gland in dogs and toads during the early 1940s. In 1947 he was awarded the Nobel Prize for his achievement. He was the first Latin American to receive the Nobel Laureate in the sciences. The award was particularly poignant given that four years before the Argentinian military government had Houssay dismissed from his position at the University of Buenos Aires Medical school where he had built up an internationally respected department in experimental physiology and medicine from 1919. Houssay was later reinstated in 1955 following Juan Peron's fall from power.1971-09-21T00:00:00+0000Gwei-djen was a Chinese biochemist who undertook pioneering work on metabolic pathways. In 1933, Gwei-djen took the bold decision to leave China, then isolated from the West, to study for a doctorate at Cambridge University where she remained for the rest of her career. By 1939 she had developed the first sensitive assay for detecting low levels of pyruvic acid, an intermediate involved in the breakdown of carbohydrates. Her work demonstrated that the levels of pyruvic acid could be raised by vitamin B1 deficiency and exercise. Gwei-djen worked closely with both Dorothy and Joseph Needham. Together with Joseph she compiled a series of books detailing Chinese achievements in science and technology. 1991-11-28T00:00:00+0000
Date Event People Places
12 Apr 1884Otto F Meyerhof was born in Hanover, GermanyMeyerhofKiel University, University of Pennsylvania
10 Apr 1887Bernardo Alberto Houssay was born in Buenos Aires, ArgentinaHoussayUniversity of Buenos Aires
22 Jul 1904Lu Gwei-djen was born in Nanjing, Qing ChinaGwei-djen University of Cambridge
1929Carl and Gerty Cori outlined the body's metabolic pathway to break down some carbohydrates, like glycogen, and synthesise othersCarl Cori, Gerty CoriRoswell Park Cancer Institute
6 Oct 1951Otto F Meyerhof diedMeyerhofKiel University, University of Pennsylvania
21 Sep 1971Bernardo Alberto Houssay diedHoussayUniversity of Buenos Aires
28 Nov 1991Lu Gwei-djen diedGwei-djenUniversity of Cambridge

12 Apr 1884

Otto F Meyerhof was born in Hanover, Germany

10 Apr 1887

Bernardo Alberto Houssay was born in Buenos Aires, Argentina

22 Jul 1904

Lu Gwei-djen was born in Nanjing, Qing China

1929

Carl and Gerty Cori outlined the body's metabolic pathway to break down some carbohydrates, like glycogen, and synthesise others

6 Oct 1951

Otto F Meyerhof died

21 Sep 1971

Bernardo Alberto Houssay died

28 Nov 1991

Lu Gwei-djen died

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