Timeline of key events in biotechnology
Mouseover the event title for a more detailed description of the event (if available). To search for particular terms in the description of the event enter the term in the box below 'Event' on the table and press 'enter'. Alternatively use the dropdown lists to filter by Person, Place or Science. Click here to clear the filter.
Date | Event | People | Places | Sciences |
---|---|---|---|---|
27 Aug 2021 | Edmond H Fischer died | Fischer | University of Washington | Biochemistry |
25 Sep 2021 | First genetically engineered pig kidney successfully transplanted into a brain-dead human patient | Robert Montgomery | New York University | Transplant, Transgenic animals |
8 Dec 2021 | FDA issued emergency authorisation for long-acting monoclonal antibodies for pre-exposure prevention of COVID-19 in certain patients | AstraZeneca | Monoclonal antibodies | |
6 Jan 2022 | mRNA technology shown to successfully reprogramme T lymphocyptes in mice to treat cardiac injury | Rurik, Tombacz, Yadegari, Mendez Fernandez, Shewale, Li Li, Kimura, Younoss Soliman, Papp, Ying Tam, Mui, Pure, June, Bghajanian, Drew Weissman, Parhiz, Jonathan Epstein | University of Pennsylvania | mRNA |
11 Jan 2022 | First pig-to-human heart transplant | Mohiuddin | University of Maryland | Transplants, Transgenic animals |
26 Jan 2022 | First mRNA vaccine for HIV begins trials in humans | Scripps Research Institute, Moderna, George Washington University School of Medicine | mRNA | |
11 Feb 2022 | FDA issued emergency use authorisation for a new monoclonal antibody treatment for COVID-19 that is active against the omicron variant. | AbCellera, Eli Lilly | Monoclonal antibodies | |
23 Feb 2022 | Human Lung Alveolus Chip demonstrated drug to significantly inhibit production of inflammation-causing cytokines triggered by SARS-CoV-2 and other viral infections | Ingber | Harvard University, Wyss Institute, Cantex Pharmaceuticals | Organ-on-a-chip |
5 Apr 2022 | Sidney Altman died | Altman | Harvard University, Laboratory of Molecular Biology, Yale University | RNA, genetics |
8 Apr 2022 | Human lung aveolus chip reveals mechanical control of immune responses against viral infection | Haiqing Bai, Longlong Si, Amanda Jiang, Chaitra Belgur, Yunhao Zhai, Plebani, Crystal Yuri Oh, Melissa Rodas, Patil, Nurani, Gilpin, Rani Powers, Girija Goyal, Prantil-Baun, Ingber | Harvard University, Wyss Institute, University of Chieti-Pescara | Organ-on-a-chip |
19 Apr 2022 | First Organ-on-a-chip used in FDA Investigational New Drug application to get authorisation for testing a drug in a clinical trial | Hickman, Shuler | Hesperos, Cornell University | Organ-on-a-chip |
27 Apr 2022 | Gene therapy shown to restore fertility in congenitally infertile mice | Kanatsu-Shinohara, Jiyoung Lee, o Miyazaki, Morimoto, Shinohara | Kyoto University, Tokyo Medical and Dental University | Gene therapy, Reproduction |
19 May 2022 | Phase I trial launched with mRNA vaccine against HIV in Africa | Scripps Research Institute, Moderna | mRNA, vaccines | |
17 Aug 2022 | FDA approved gene therapy for beta thalassemia treatment | Bluebird | Gene therapy | |
31 Aug 2022 | NICE gives green light for FMT to be used to resolve recurrent Clostridium difficile infections | Faecal microbiota transplant | ||
14 Sep 2022 | First phase 3 efficacy trial launched with mRNA-based influenza vaccine | Pfizer | mRNA, vaccines | |
27 Sep 2022 | FDA gives Vertex green light to submit rolling application for review of CRISPR based therapy to treat sickle cell disease and beta thalassemia | Crispr-Cas9, Gene editing | ||
10 Nov 2022 | Small clinical trial shows CRISPR promising tool for editing immune cells to enhance their capacity to destroy cancer cells | Foy, Ribas, Mandl | PACT Pharma | Crispr-Cas9, Gene editing |
23 Nov 2022 | New CRISPR gene editing tools found in thousands of phages | Al-Shayeb, Skopintsev, Soczek, Stahl,Zheng Li, Smock, Eggers, Pausch, Cress, Huang, Staskawicz, Savage,Jacobsen, Banfield, Doudna | University of California Berkeley | Crispr-Cas9, Gene editing, Bacteriophages |
14 Dec 2022 | First randomised-trial testing of mRNA vaccine for cancer to boost immunotherapy reported to be promising in patients with metastatic skin cancer | Moderna, Merck | mRNA, immune checkpoint inhibitors, cancer immunotherapy | |
27 Aug 2021
Edmond H Fischer died
25 Sep 2021
First genetically engineered pig kidney successfully transplanted into a brain-dead human patient
8 Dec 2021
FDA issued emergency authorisation for long-acting monoclonal antibodies for pre-exposure prevention of COVID-19 in certain patients
6 Jan 2022
mRNA technology shown to successfully reprogramme T lymphocyptes in mice to treat cardiac injury
11 Jan 2022
First pig-to-human heart transplant
26 Jan 2022
First mRNA vaccine for HIV begins trials in humans
11 Feb 2022
FDA issued emergency use authorisation for a new monoclonal antibody treatment for COVID-19 that is active against the omicron variant.
23 Feb 2022
Human Lung Alveolus Chip demonstrated drug to significantly inhibit production of inflammation-causing cytokines triggered by SARS-CoV-2 and other viral infections
5 Apr 2022
Sidney Altman died
8 Apr 2022
Human lung aveolus chip reveals mechanical control of immune responses against viral infection
19 Apr 2022
First Organ-on-a-chip used in FDA Investigational New Drug application to get authorisation for testing a drug in a clinical trial
27 Apr 2022
Gene therapy shown to restore fertility in congenitally infertile mice
19 May 2022
Phase I trial launched with mRNA vaccine against HIV in Africa
17 Aug 2022
FDA approved gene therapy for beta thalassemia treatment
31 Aug 2022
NICE gives green light for FMT to be used to resolve recurrent Clostridium difficile infections
14 Sep 2022
First phase 3 efficacy trial launched with mRNA-based influenza vaccine
27 Sep 2022
FDA gives Vertex green light to submit rolling application for review of CRISPR based therapy to treat sickle cell disease and beta thalassemia
10 Nov 2022
Small clinical trial shows CRISPR promising tool for editing immune cells to enhance their capacity to destroy cancer cells
23 Nov 2022
New CRISPR gene editing tools found in thousands of phages
14 Dec 2022
First randomised-trial testing of mRNA vaccine for cancer to boost immunotherapy reported to be promising in patients with metastatic skin cancer
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