CRISPR-Cas9: Timeline of key events

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The advantage of the technique is it enables scientists to disable specific genes and correct harmful mutations by providing cells with fresh DNA strands with to repair the cut. Unlike Crispr-Cas9, which chops target DNA in half, prime editing nicks it and then writes a new section of DNA into the specified region. The new procedure was published in AW Anzalone et al, 'Search-and-replace genome editing without double-strand breaks or donor DNA', Nature (2019), https://doi.org/10.1038/s41586-019-1711-42019-10-21T00:00:00+0000He Jiankui, who used the gene-editing technology to make twin babies immune to HIV by altering gene CCR5, was sentenced to three years in prison by a Chinese court and fined around $430,000. 2019-12-30T00:00:00+0000
Date Event People Places Sciences
21 Oct 2019New DNA editing technique called 'prime editing' publishedAnzalone, Randolph, Davis, Sousa, Koblan, Levy, Chen, Wilson, Newby, Ranguram, LiuMassachusetts Institute of Technology, Harvard UniversityCrispr-Cas9, Gene editing,
30 Dec 2019Chinese scientist convicted for using CRISPR-Cas9 in human babiesJiankuiSouthern University of Science and Technology of ChinaCrispr-Cas9, Gene editing,

21 Oct 2019

New DNA editing technique called 'prime editing' published

30 Dec 2019

Chinese scientist convicted for using CRISPR-Cas9 in human babies

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