Immunotherapy: Timeline of key events
Mouseover the event title for a more detailed description of the event (if available). To search for particular terms in the description of the event enter the term in the box below 'Event' on the table and press 'enter'. Alternatively use the dropdown lists to filter by Person, Place or Science. Click here to clear the filter.
Date | Event | People | Places | Sciences |
---|---|---|---|---|
23 Mar 2017 | FDA granted accelerated approval to avelumab, a PD-L1 checkpoint inhibitor, to treat Merkel cell carcinoma, a rare form of skin cancer treatment, in patients 12 years and older with metastatic Merkel cell carcinoma, a rare form of skin disorder | EMD Serono, Merck KGaA, Pfizer | Immune checkpoint inhibitors, Cancer immunotherapy, Oncology, Monoclonal antibodies | |
12 Jul 2017 | US FDA Oncologic Drugs Advisory Committee recommended the approval of the first adoptive cell therapy (CAR-T cell therapy) for B cell acute leukaemia | June | Novartis, University of Pennsylvania | Cancer immunotherapy, Oncology, Adoptive cell therapy, Gene therapy |
30 Aug 2017 | USA FDA approved CAR-T therapy for certain pediatric and young adult patients with a form of acute lymphoblastic leukemia | June | Novartis, University of Pennsylvania | Cancer immunotherapy, Oncology, Adoptive cell therapy, Gene therapy |
20 Sep 2017 | Nivolumab (Opdivo®) made available for NHS patients with advanced lung cancer | Honko, Freeman | Medarex, Bristol-Myers Squibb, Ono Pharmaceutical | Immune checkpoint inhibitors, Immunotherapy, Monoclonal antibodies |
2 Nov 2017 | Cancer patients taking routine antibiotics before or soon after given PD-1 checkpoint inhibitor found to relapse quicker and have shorter survival time | Zitvogel, Kroemer | Institut Gustave Roussy | Cancer immunotherapy, Immune checkpoint inhibitors, Oncology, Microbiome |
2 Nov 2017 | Experiments with mice show tumour growth can be reduced by giving faecal transplants from patients who positively responded to cancer immunotherapy | Wargo, Gopalakrishnan | MD Anderson Cancer Center, Institute Gustave-Roussy | Cancer immunotherapy, Immune checkpoint inhibitors, Oncology, Microbiome |
1 Oct 2018 | James Allison and Tasuku Honjo were awarded the Nobel Prize in Physiology or Medicine for their discovery of immune checkpoint inhibitors for cancer therapy | Allison, Honjo | University of Texas MD Anderson Cancer Center, Kyoto University | Cancer immunotherapy, Immune checkpoint inhibitors, Oncology |
16 Nov 2018 | Virus genetically engineered to kill cancer cells opening new immunotherapy avenue | Freedman, Duffy, Lei-Rossman, Muntzer, Scott, Hagel, Campo, Bryant, Verrill, Lambert, Miller, Champion, Seymour, Fisher, Richardson | Oxford University | Cancer immunotherapy |
7 Dec 2018 | Mouse and human skin cells reprogrammed into immune cells to fight cancer | Rosa, Pires, Kurtochkin, Ferreira, Gomes, Palma, Shaiv, Solanas, Azenha, Papatsenko, Schulz, Reis e Sousa, Carlos-Filipe | Lund University, Skolkovo Institute of Science and Technology, Francis Crick Institute | Cancer immunotherapy, Stem cells |
14 Dec 2022 | First randomised-trial testing of mRNA vaccine for cancer to boost immunotherapy reported to be promising in patients with metastatic skin cancer | Moderna, Merck | mRNA, immune checkpoint inhibitors, cancer immunotherapy | |
23 Mar 2017
FDA granted accelerated approval to avelumab, a PD-L1 checkpoint inhibitor, to treat Merkel cell carcinoma, a rare form of skin cancer treatment, in patients 12 years and older with metastatic Merkel cell carcinoma, a rare form of skin disorder
12 Jul 2017
US FDA Oncologic Drugs Advisory Committee recommended the approval of the first adoptive cell therapy (CAR-T cell therapy) for B cell acute leukaemia
30 Aug 2017
USA FDA approved CAR-T therapy for certain pediatric and young adult patients with a form of acute lymphoblastic leukemia
20 Sep 2017
Nivolumab (Opdivo®) made available for NHS patients with advanced lung cancer
2 Nov 2017
Cancer patients taking routine antibiotics before or soon after given PD-1 checkpoint inhibitor found to relapse quicker and have shorter survival time
2 Nov 2017
Experiments with mice show tumour growth can be reduced by giving faecal transplants from patients who positively responded to cancer immunotherapy
1 Oct 2018
James Allison and Tasuku Honjo were awarded the Nobel Prize in Physiology or Medicine for their discovery of immune checkpoint inhibitors for cancer therapy
16 Nov 2018
Virus genetically engineered to kill cancer cells opening new immunotherapy avenue
7 Dec 2018
Mouse and human skin cells reprogrammed into immune cells to fight cancer
14 Dec 2022
First randomised-trial testing of mRNA vaccine for cancer to boost immunotherapy reported to be promising in patients with metastatic skin cancer
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